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Helicase-inactivating mutations as a basis for dominant negative phenotypes
There is ample evidence from studies of both unicellular and multicellular organisms that helicase-inactivating mutations lead to cellular dysfunction and disease phenotypes. In this review, we will discuss the mechanisms underlying the basis for abnormal phenotypes linked to mutations in genes enco...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Landes Bioscience
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3055193/ https://ncbi.nlm.nih.gov/pubmed/20980836 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.9.20.13667 |
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