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Helicase-inactivating mutations as a basis for dominant negative phenotypes

There is ample evidence from studies of both unicellular and multicellular organisms that helicase-inactivating mutations lead to cellular dysfunction and disease phenotypes. In this review, we will discuss the mechanisms underlying the basis for abnormal phenotypes linked to mutations in genes enco...

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Hlavní autoři: Wu, Yuliang, Brosh, Robert M
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3055193/
https://ncbi.nlm.nih.gov/pubmed/20980836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.9.20.13667
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