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Starvation promotes REV1 SUMOylation and p53-dependent sensitization of melanoma and breast cancer cells

Short-term starvation or fasting can augment cancer treatment efficacy and can be effective in delaying cancer progression in the absence of chemotherapy, but the underlying molecular mechanisms of action remain elusive. Here we describe the role of REV1, a specialized DNA polymerase involved in DNA...

詳細記述

保存先:
書誌詳細
出版年:Cancer Res
主要な著者: Shim, Hong Seok, Wei, Min, Brandhorst, Sebastian, Longo, Valter D.
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4359966/
https://ncbi.nlm.nih.gov/pubmed/25614517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-2249
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