Fasting regulates EGR1 and protects from glucose- and dexamethasone-dependent sensitization to chemotherapy

Fasting reduces glucose levels and protects mice against chemotoxicity, yet drugs that promote hyperglycemia are widely used in cancer treatment. Here, we show that dexamethasone (Dexa) and rapamycin (Rapa), commonly administered to cancer patients, elevate glucose and sensitize cardiomyocytes and m...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS Biol
Egile Nagusiak: Di Biase, Stefano, Shim, Hong Seok, Kim, Kyung Hwa, Vinciguerra, Manlio, Rappa, Francesca, Wei, Min, Brandhorst, Sebastian, Cappello, Francesco, Mirzaei, Hamed, Lee, Changhan, Longo, Valter D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2017
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5373519/
https://ncbi.nlm.nih.gov/pubmed/28358805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2001951
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