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Genetic variation in human DNA replication timing
Genomic DNA replicates in a choreographed temporal order that impacts the distribution of mutations along the genome. We show here that DNA replication timing is shaped by genetic polymorphisms that act in cis upon megabase-scale DNA segments. In genome sequences from proliferating cells, read depth...
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| Pubblicato in: | Cell |
|---|---|
| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4359889/ https://ncbi.nlm.nih.gov/pubmed/25416942 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.10.025 |
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