Genetic variation in human DNA replication timing

Genomic DNA replicates in a choreographed temporal order that impacts the distribution of mutations along the genome. We show here that DNA replication timing is shaped by genetic polymorphisms that act in cis upon megabase-scale DNA segments. In genome sequences from proliferating cells, read depth...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Cell
Asıl Yazarlar: Koren, Amnon, Handsaker, Robert E., Kamitaki, Nolan, Karlić, Rosa, Ghosh, Sulagna, Polak, Paz, Eggan, Kevin, McCarroll, Steven A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4359889/
https://ncbi.nlm.nih.gov/pubmed/25416942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.10.025
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