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Germline Structural Variations Are Preferential Sites of DNA Replication Timing Plasticity during Development

The DNA replication timing program is modulated throughout development and is also one of the main factors influencing the distribution of mutation rates across the genome. However, the relationship between the mutagenic influence of replication timing and its developmental plasticity remains unexpl...

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Detalhes bibliográficos
Publicado no:Genome Biol Evol
Main Authors: Hulke, Michelle L, Siefert, Joseph C, Sansam, Christopher L, Koren, Amnon
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6582765/
https://ncbi.nlm.nih.gov/pubmed/31076752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gbe/evz098
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