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Germline Structural Variations Are Preferential Sites of DNA Replication Timing Plasticity during Development

The DNA replication timing program is modulated throughout development and is also one of the main factors influencing the distribution of mutation rates across the genome. However, the relationship between the mutagenic influence of replication timing and its developmental plasticity remains unexpl...

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Bibliographische Detailangaben
Veröffentlicht in:Genome Biol Evol
Hauptverfasser: Hulke, Michelle L, Siefert, Joseph C, Sansam, Christopher L, Koren, Amnon
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6582765/
https://ncbi.nlm.nih.gov/pubmed/31076752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gbe/evz098
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