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Genomic methods for measuring DNA replication dynamics

Genomic DNA replicates according to a defined temporal program in which early-replicating loci are associated with open chromatin, higher gene density and increased gene expression levels, while late-replicating loci tend to be heterochromatic and show higher rates of genomic instability. The abilit...

詳細記述

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書誌詳細
出版年:Chromosome Res
主要な著者: Hulke, Michelle L., Massey, Dashiell J., Koren, Amnon
フォーマット: Artigo
言語:Inglês
出版事項: 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7131883/
https://ncbi.nlm.nih.gov/pubmed/31848781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10577-019-09624-y
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