Differential Relationship of DNA Replication Timing to Different Forms of Human Mutation and Variation

Human genetic variation is distributed nonrandomly across the genome, though the principles governing its distribution are only partially known. DNA replication creates opportunities for mutation, and the timing of DNA replication correlates with the density of SNPs across the human genome. To enabl...

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Autores principales: Koren, Amnon, Polak, Paz, Nemesh, James, Michaelson, Jacob J., Sebat, Jonathan, Sunyaev, Shamil R., McCarroll, Steven A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2012
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3516607/
https://ncbi.nlm.nih.gov/pubmed/23176822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2012.10.018
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