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Differential Relationship of DNA Replication Timing to Different Forms of Human Mutation and Variation

Human genetic variation is distributed nonrandomly across the genome, though the principles governing its distribution are only partially known. DNA replication creates opportunities for mutation, and the timing of DNA replication correlates with the density of SNPs across the human genome. To enabl...

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Bibliografske podrobnosti
Main Authors: Koren, Amnon, Polak, Paz, Nemesh, James, Michaelson, Jacob J., Sebat, Jonathan, Sunyaev, Shamil R., McCarroll, Steven A.
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3516607/
https://ncbi.nlm.nih.gov/pubmed/23176822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2012.10.018
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