The Cys18-Cys137 Disulfide Bond in Mouse Angiotensinogen Does Not Affect AngII-dependent Functions In Vivo

Renin cleavage of angiotensinogen (AGT) releases angiotensin I (AngI) in the initial step of producing all angiotensin peptides. It has been suggested recently that redox regulation of a disulfide bond in AGT involving Cys18-Cys137 may be important to its renin cleavage efficiency in vivo. The purpo...

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Publicado no:Hypertension
Main Authors: Wu, Congqing, Xu, Yinchuan, Lu, Hong, Howatt, Deborah A., Balakrishnan, Anju, Moorleghen, Jessica J., Vander Kooi, Craig W., Cassis, Lisa A., Wang, Jian-an, Daugherty, Alan
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4359061/
https://ncbi.nlm.nih.gov/pubmed/25691624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.115.05166
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