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Comparative Metabolic Analysis of CHO Cell Clones Obtained through Cell Engineering, for IgG Productivity, Growth and Cell Longevity

Cell engineering has been used to improve animal cells’ central carbon metabolism. Due to the central carbon metabolism’s inefficiency and limiting input of carbons into the TCA cycle, key reactions belonging to these pathways have been targeted to improve cultures’ performance. Previous works have...

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書誌詳細
出版年:PLoS One
主要な著者: Wilkens, Camila A., Gerdtzen, Ziomara P.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4358941/
https://ncbi.nlm.nih.gov/pubmed/25768021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0119053
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