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Radioprotective efficacy and toxicity of a new family of aminothiol analogs
PURPOSE: A family of 17 new nucleophilic-polyamine and aminothiol structures was designed and synthesized to identify new topical or systemic radioprotectors with acceptable mammalian toxicity profiles. Design elements included: (i) Length and charge of the DNA-interacting, alkylamine backbone, (ii)...
Guardado en:
| Publicado en: | Int J Radiat Biol |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2013
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4358772/ https://ncbi.nlm.nih.gov/pubmed/23369131 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/09553002.2013.770579 |
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