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Synthesis and Growth Regulatory Activity of a Prototype Member of a New Family of Aminothiol Radioprotectors

The synthesis, growth inhibition and radioprotective activity of the PrC-210 aminothiol, 3-(methylamino)-2-((methylamino)methyl)propane-1-thiol, and its polyamine and thiolated polyamine progenitors are reported. All of the molecules significantly inhibited growth of cultured normal human fibroblast...

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Bibliographic Details
Main Authors: Copp, Richard R., Peebles, Daniel D., Fahl, William E.
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3254260/
https://ncbi.nlm.nih.gov/pubmed/22041059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2011.10.011
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