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Conformational changes in chromatin structure induced by the radioprotective aminothiol, WR 1065.

WR 1065, 2-[(minopropyl) amino] ethanethiol is an effective scavenger of free radicals. When present during irradiation it reduces cellular DNA damage as analysed by alkaline elution from filters. The same technique indicates that without irradiation, WR 1065 has no effect of DNA integrity. Using nu...

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Détails bibliographiques
Auteurs principaux: Vaughan, A. T., Grdina, D. J., Meechan, P. J., Milner, A. E., Gordon, D. J.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 1989
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2247278/
https://ncbi.nlm.nih.gov/pubmed/2605099
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