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Postsynaptic P2X3-containing receptors in gustatory nerve fibres mediate responses to all taste qualities in mice

Taste buds release ATP to activate ionotropic purinoceptors composed of P2X2 and P2X3 subunits, present on the taste nerves. Mice with genetic deletion of P2X2 and P2X3 receptors (double knockout mice) lack responses to all taste stimuli presumably due to the absence of ATP-gated receptors on the af...

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Publicado en:J Physiol
Autores principales: Vandenbeuch, Aurelie, Larson, Eric D, Anderson, Catherine B, Smith, Steven A, Ford, Anthony P, Finger, Thomas E, Kinnamon, Sue C
Formato: Artigo
Lenguaje:Inglês
Publicado: BlackWell Publishing Ltd 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4358674/
https://ncbi.nlm.nih.gov/pubmed/25524179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2014.281014
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