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Presenilin-like GxGD Membrane Proteases Have Dual Roles as Proteolytic Enzymes and Ion Channels

The GxGD proteases function to cleave protein substrates within the membrane. As these proteases contain multiple transmembrane domains typical of ion channels, we examined if GxGD proteases also function as ion channels. We tested the putative dual function by examining two archeobacterial GxGD pro...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Kuo, Ivana Y., Hu, Jian, Ha, Ya, Ehrlich, Barbara E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4358277/
https://ncbi.nlm.nih.gov/pubmed/25609250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.629584
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