Akt-mediated phosphorylation of Oct4 is associated with the proliferation of stem-like cancer cells

Oct4 protein encoded by POU5F1 plays a pivotal role in maintaining the self-renewal of pluripotent stem cells; however, its presence in cancer cells remains controversial. In the present study, we provided evidence that the transcripts of authentic OCT4 gene (OCT4A) and its multiple pseudogenes were...

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Pubblicato in:Oncol Rep
Autori principali: ZHAO, QING-WEI, ZHOU, YAN-WEN, LI, WEN-XIN, KANG, BO, ZHANG, XIAO-QIAN, YANG, YING, CHENG, JIE, YIN, SHENG-YONG, TONG, YING, HE, JIAN-QIN, YAO, HANG-PING, ZHENG, MIN, WANG, YING-JIE
Natura: Artigo
Lingua:Inglês
Pubblicazione: D.A. Spandidos 2015
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4358081/
https://ncbi.nlm.nih.gov/pubmed/25625591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2015.3752
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