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Dynamic Escherichia coli SeqA complexes organize the newly replicated DNA at a considerable distance from the replisome

The Escherichia coli SeqA protein binds to newly replicated, hemimethylated DNA behind replication forks and forms structures consisting of several hundred SeqA molecules bound to about 100 kb of DNA. It has been suggested that SeqA structures either direct the new sister DNA molecules away from eac...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Main Authors: Helgesen, Emily, Fossum-Raunehaug, Solveig, Sætre, Frank, Schink, Kay Oliver, Skarstad, Kirsten
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4357733/
https://ncbi.nlm.nih.gov/pubmed/25722374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv146
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