MERIT40 deficiency expands hematopoietic stem cell pools by regulating thrombopoietin receptor signaling

Hematopoietic stem cell (HSC) self-renewal and multilineage reconstitution are controlled by positive and negative signaling cues with perturbations leading to disease. Lnk is an essential signaling adaptor protein that dampens signaling by the cytokine thrombopoietin (Tpo) to limit HSC expansion. H...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Blood
Main Authors: Rozenova, Krasimira, Jiang, Jing, Donaghy, Ryan, Aressy, Bernadette, Greenberg, Roger A., Tong, Wei
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2015
Fag:
Hematopoiesis and Stem Cells
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4357581/
https://ncbi.nlm.nih.gov/pubmed/25636339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-07-588145
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker