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Conquering 2-Aminopurine’s Deficiencies: Highly Emissive Isomorphic Guanosine Surrogate Faithfully Monitors Guanosine Conformation and Dynamics in DNA

The archetypical fluorescent nucleoside analog, 2-aminopurine (2Ap) has been used in countless assays, though it suffers from very low quantum yield, especially when included in double strands, and from the fact that its residual emission frequently does not represent biologically relevant conformat...

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Podrobná bibliografie
Vydáno v:J Am Chem Soc
Hlavní autoři: Sholokh, Marianna, Sharma, Rajhans, Shin, Dongwon, Das, Ranjan, Zaporozhets, Olga A., Tor, Yitzhak, Mély, Yves
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4357565/
https://ncbi.nlm.nih.gov/pubmed/25714036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja513107r
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