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Monitoring translation with modified mRNAs strategically labeled with isomorphic fluorescent guanosine mimetics
Here we examine three mRNAs, site-specifically modified at codon positions 4, 5, and 6 with a new emissive and responsive isosteric guanosine mimetic ((th)G), with the goal of developing real time assays for monitoring translation-related events at nucleotide resolution. All three emissive mRNAs tes...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3783585/ https://ncbi.nlm.nih.gov/pubmed/23865809 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb400256h |
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