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On the Role of Protein Disulfide Isomerase in the Retrograde Cell Transport of Secreted Phospholipases A(2)
Following the finding that ammodytoxin (Atx), a neurotoxic secreted phospholipase A(2) (sPLA(2)) in snake venom, binds specifically to protein disulfide isomerase (PDI) in vitro we show that these proteins also interact in living rat PC12 cells that are able to internalize this group IIA (GIIA) sPLA...
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| Publié dans: | PLoS One |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4357439/ https://ncbi.nlm.nih.gov/pubmed/25763817 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120692 |
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