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On the Role of Protein Disulfide Isomerase in the Retrograde Cell Transport of Secreted Phospholipases A(2)
Following the finding that ammodytoxin (Atx), a neurotoxic secreted phospholipase A(2) (sPLA(2)) in snake venom, binds specifically to protein disulfide isomerase (PDI) in vitro we show that these proteins also interact in living rat PC12 cells that are able to internalize this group IIA (GIIA) sPLA...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4357439/ https://ncbi.nlm.nih.gov/pubmed/25763817 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120692 |
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