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Mst1 inhibition rescues β(1)-adrenergic cardiomyopathy by reducing myocyte necrosis and non-myocyte apoptosis rather than myocyte apoptosis
It is generally held that inhibition of mammalian sterile 20-like kinase 1 (Mst1) protects the heart through reducing myocyte apoptosis. We determined whether inhibition with a dominant-negative Mst1 (DN-Mst1) would protect against the cardiomyopathy induced by chronic β(1)-adrenergic receptor (β(1)...
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| Publicado en: | Basic Res Cardiol |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4357177/ https://ncbi.nlm.nih.gov/pubmed/25600225 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00395-015-0461-1 |
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