Identification of subgroup-specific miRNA patterns by epigenetic profiling of sporadic and Lynch syndrome-associated colorectal and endometrial carcinoma

BACKGROUND: Altered expression of microRNAs (miRNAs) commonly accompanies colorectal (CRC) and endometrial carcinoma (EC) development, but the underlying mechanisms and clinicopathological correlations remain to be clarified. We focused on epigenetic mechanisms and aimed to explore if DNA methylatio...

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Veröffentlicht in:Clin Epigenetics
Hauptverfasser: Kaur, Sippy, Lotsari, Johanna E, Al-Sohaily, Sam, Warusavitarne, Janindra, Kohonen-Corish, Maija RJ, Peltomäki, Päivi
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4357086/
https://ncbi.nlm.nih.gov/pubmed/25767621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-015-0059-3
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