Identification of subgroup-specific miRNA patterns by epigenetic profiling of sporadic and Lynch syndrome-associated colorectal and endometrial carcinoma

BACKGROUND: Altered expression of microRNAs (miRNAs) commonly accompanies colorectal (CRC) and endometrial carcinoma (EC) development, but the underlying mechanisms and clinicopathological correlations remain to be clarified. We focused on epigenetic mechanisms and aimed to explore if DNA methylatio...

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Détails bibliographiques
Publié dans:Clin Epigenetics
Auteurs principaux: Kaur, Sippy, Lotsari, Johanna E, Al-Sohaily, Sam, Warusavitarne, Janindra, Kohonen-Corish, Maija RJ, Peltomäki, Päivi
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2015
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4357086/
https://ncbi.nlm.nih.gov/pubmed/25767621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-015-0059-3
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