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The Nuclear Receptor Nr4a1 Controls CD8 T Cell Development Through Transcriptional Suppression of Runx3

The NR4A nuclear receptor family member Nr4a1 is strongly induced in thymocytes undergoing selection, and has been shown to control the development of T(reg) cells; however the role of Nr4a1 in CD8(+) T cells remains undefined. Here we report a novel role for Nr4a1 in regulating the development and...

詳細記述

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書誌詳細
出版年:Sci Rep
主要な著者: Nowyhed, Heba N., Huynh, Tridu R., Blatchley, Amy, Wu, Runpei, Thomas, Graham D., Hedrick, Catherine C.
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4356985/
https://ncbi.nlm.nih.gov/pubmed/25762306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep09059
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