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Construction of stable packaging cell lines for clinical lentiviral vector production

Lentiviral vectors are useful experimental tools for stable gene delivery and have been used to treat human inherited genetic disorders and hematologic malignancies with promising results. Because some of the lentiviral vector components are cytotoxic, transient plasmid transfection has been used to...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Sanber, Khaled S., Knight, Sean B., Stephen, Sam L., Bailey, Ranbir, Escors, David, Minshull, Jeremy, Santilli, Giorgia, Thrasher, Adrian J., Collins, Mary K., Takeuchi, Yasuhiro
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4356972/
https://ncbi.nlm.nih.gov/pubmed/25762005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep09021
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