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Construction of stable packaging cell lines for clinical lentiviral vector production

Lentiviral vectors are useful experimental tools for stable gene delivery and have been used to treat human inherited genetic disorders and hematologic malignancies with promising results. Because some of the lentiviral vector components are cytotoxic, transient plasmid transfection has been used to...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Sanber, Khaled S., Knight, Sean B., Stephen, Sam L., Bailey, Ranbir, Escors, David, Minshull, Jeremy, Santilli, Giorgia, Thrasher, Adrian J., Collins, Mary K., Takeuchi, Yasuhiro
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2015
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4356972/
https://ncbi.nlm.nih.gov/pubmed/25762005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep09021
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