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Construction of stable packaging cell lines for clinical lentiviral vector production

Lentiviral vectors are useful experimental tools for stable gene delivery and have been used to treat human inherited genetic disorders and hematologic malignancies with promising results. Because some of the lentiviral vector components are cytotoxic, transient plasmid transfection has been used to...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Sanber, Khaled S., Knight, Sean B., Stephen, Sam L., Bailey, Ranbir, Escors, David, Minshull, Jeremy, Santilli, Giorgia, Thrasher, Adrian J., Collins, Mary K., Takeuchi, Yasuhiro
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4356972/
https://ncbi.nlm.nih.gov/pubmed/25762005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep09021
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