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HSV-1 Remodels Host Telomeres To Facilitate Viral Replication
Telomeres protect the ends of cellular chromosomes. We show here that infection with herpes simplex virus 1 (HSV-1) results in chromosomal structural aberrations at telomeres and the accumulation of telomere dysfunction-induced DNA damage foci (TIFs). At the molecular level, HSV-1 induces transcript...
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| Publicado no: | Cell Rep |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4356630/ https://ncbi.nlm.nih.gov/pubmed/25497088 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.11.019 |
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