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The Replisome Pausing Factor Timeless Is Required for Episomal Maintenance of Latent Epstein-Barr Virus

The Epstein-Barr virus (EBV) genome is maintained as an extrachromosomal episome during latent infection of B lymphocytes. Episomal maintenance is conferred by the interaction of the EBV-encoded nuclear antigen 1 (EBNA1) with a tandem array of high-affinity binding sites, referred to as the family o...

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Autors principals: Dheekollu, Jayaraju, Lieberman, Paul M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126297/
https://ncbi.nlm.nih.gov/pubmed/21490103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02425-10
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