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Establishment of Latent Epstein-Barr Virus Infection and Stable Episomal Maintenance in Murine B-Cell Lines

Epstein-Barr virus (EBV) is a strict human pathogen for which no small animal models exist. Plasmids that contain the EBV plasmid origin of replication, oriP, and express EBV nuclear antigen 1 (EBNA1) are stably maintained extrachromosomally in human cells, whereas these plasmids replicate poorly in...

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Detalhes bibliográficos
Main Authors: Haan, Keith M., Aiyar, Ashok, Longnecker, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC115929/
https://ncbi.nlm.nih.gov/pubmed/11222728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.6.3016-3020.2001
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