Interference with T cell receptor–HLA-DR interactions by Epstein–Barr virus gp42 results in reduced T helper cell recognition

Epstein–Barr virus (EBV) persists lifelong in infected hosts despite the presence of antiviral immunity. Many viral antigens are expressed during lytic infection. Thus, for EBV to spread, it must have evolved effective ways to evade immune recognition. Here, we report that HLA class II-restricted an...

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Autors principals: Ressing, Maaike E., van Leeuwen, Daphne, Verreck, Frank A. W., Gomez, Raquel, Heemskerk, Bianca, Toebes, Mireille, Mullen, Maureen M., Jardetzky, Theodore S., Longnecker, Richard, Schilham, Marco W., Ottenhoff, Tom H. M., Neefjes, Jacques, Schumacher, Ton N., Hutt-Fletcher, Lindsey M., Wiertz, Emmanuel J. H. J.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2003
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC208801/
https://ncbi.nlm.nih.gov/pubmed/14504389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2034960100
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