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Interference with T cell receptor–HLA-DR interactions by Epstein–Barr virus gp42 results in reduced T helper cell recognition

Epstein–Barr virus (EBV) persists lifelong in infected hosts despite the presence of antiviral immunity. Many viral antigens are expressed during lytic infection. Thus, for EBV to spread, it must have evolved effective ways to evade immune recognition. Here, we report that HLA class II-restricted an...

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Gorde:
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Ressing, Maaike E., van Leeuwen, Daphne, Verreck, Frank A. W., Gomez, Raquel, Heemskerk, Bianca, Toebes, Mireille, Mullen, Maureen M., Jardetzky, Theodore S., Longnecker, Richard, Schilham, Marco W., Ottenhoff, Tom H. M., Neefjes, Jacques, Schumacher, Ton N., Hutt-Fletcher, Lindsey M., Wiertz, Emmanuel J. H. J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2003
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC208801/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14504389/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.2034960100
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