Interference with T cell receptor–HLA-DR interactions by Epstein–Barr virus gp42 results in reduced T helper cell recognition

Epstein–Barr virus (EBV) persists lifelong in infected hosts despite the presence of antiviral immunity. Many viral antigens are expressed during lytic infection. Thus, for EBV to spread, it must have evolved effective ways to evade immune recognition. Here, we report that HLA class II-restricted an...

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Hauptverfasser: Ressing, Maaike E., van Leeuwen, Daphne, Verreck, Frank A. W., Gomez, Raquel, Heemskerk, Bianca, Toebes, Mireille, Mullen, Maureen M., Jardetzky, Theodore S., Longnecker, Richard, Schilham, Marco W., Ottenhoff, Tom H. M., Neefjes, Jacques, Schumacher, Ton N., Hutt-Fletcher, Lindsey M., Wiertz, Emmanuel J. H. J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2003
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC208801/
https://ncbi.nlm.nih.gov/pubmed/14504389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2034960100
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