Epstein-Barr Virus gp42 Is Posttranslationally Modified To Produce Soluble gp42 That Mediates HLA Class II Immune Evasion

Epstein-Barr virus (EBV) resides as a persistent infection in human leukocyte antigen (HLA) class II(+) B lymphocytes and is associated with a number of malignancies. The EBV lytic-phase protein gp42 serves at least two functions: gp42 acts as the coreceptor for viral entry into B cells and hampers...

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Auteurs principaux: Ressing, Maaike E., van Leeuwen, Daphne, Verreck, Frank A. W., Keating, Sinéad, Gomez, Raquel, Franken, Kees L. M. C., Ottenhoff, Tom H. M., Spriggs, Melanie, Schumacher, Ton N., Hutt-Fletcher, Lindsey M., Rowe, Martin, Wiertz, Emmanuel J. H. J.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2005
Sujets:
Pathogenesis and Immunity
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC538541/
https://ncbi.nlm.nih.gov/pubmed/15613312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.2.841-852.2005
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