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Host shutoff during productive Epstein–Barr virus infection is mediated by BGLF5 and may contribute to immune evasion

Relatively little is known about immune evasion during the productive phase of infection by the γ(1)-herpesvirus Epstein–Barr virus (EBV). The use of a unique system to isolate cells in lytic cycle allowed us to identify a host shutoff function operating in productively EBV-infected B cells. This im...

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Huvudupphovsmän: Rowe, Martin, Glaunsinger, Britt, van Leeuwen, Daphne, Zuo, Jianmin, Sweetman, David, Ganem, Don, Middeldorp, Jaap, Wiertz, Emmanuel J. H. J., Ressing, Maaike E.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2007
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1805610/
https://ncbi.nlm.nih.gov/pubmed/17360652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611128104
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