Angiopoietin-1 Requires Oxidant Signaling through p47phox to Promote Endothelial Barrier Defense

BACKGROUND: Reactive oxygen species (ROS) are largely considered to be pathogenic to normal endothelial function in disease states such as sepsis. We hypothesized that Angiopoietin-1 (Angpt-1), an endogenous agonist of the endothelial-specific receptor, Tie-2, promotes barrier defense by activating...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Ghosh, Chandra C., Mukherjee, Aditi, David, Sascha, Milam, Katelyn E., Hunter, Jon T., Parikh, Samir M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2015
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4356555/
https://ncbi.nlm.nih.gov/pubmed/25761062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0119577
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