Llwytho...

Angiopoietin-1 requires IQGAP1 to activate Rac1 and promote endothelial barrier defense

OBJECTIVE: IQ domain GTPase-activating protein 1 (IQGAP1) contributes to cytoskeletal network regulation in epithelial cells by its scaffolding properties and by binding the Rho GTPase Rac1 to maintain its activity. The functions of IQGAP1 in endothelial cells beyond angiogenesis remain unclear. We...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: David, Sascha, Ghosh, Chandra C, Mukherjee, Aditi, Parikh, Samir M
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3249617/
https://ncbi.nlm.nih.gov/pubmed/21885850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.111.233189
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