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Angiopoietin-2 may contribute to multi-organ dysfunction and death in sepsis
OBJECTIVE: In sepsis, quiescent blood vessels become leaky and inflamed by mechanisms that are incompletely understood. We hypothesized that Angiopoietin-2 (Angpt-2), a partial antagonist of the endothelium-stabilizing receptor Tie-2 secreted by endothelium, contributes to adverse outcomes in this d...
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| Hlavní autoři: | , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3705559/ https://ncbi.nlm.nih.gov/pubmed/22890252 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCM.0b013e31825fdc31 |
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