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Excess Circulating Angiopoietin-2 May Contribute to Pulmonary Vascular Leak in Sepsis in Humans

BACKGROUND: Acute respiratory distress syndrome (ARDS) is a devastating complication of numerous underlying conditions, most notably sepsis. Although pathologic vascular leak has been implicated in the pathogenesis of ARDS and sepsis-associated lung injury, the mechanisms promoting leak are incomple...

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Autori principali: Parikh, Samir M, Mammoto, Tadanori, Schultz, Aylit, Yuan, Hai-Tao, Christiani, David, Karumanchi, S. Ananth, Sukhatme, Vikas P
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1334221/
https://ncbi.nlm.nih.gov/pubmed/16417407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.0030046
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