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Leptin Exacerbates Sepsis-Mediated Morbidity and Mortality

The adipose-derived hormone leptin is well known for its contribution to energy metabolism and satiety signaling in the hypothalamus. Previous studies suggested that obesity is an independent risk factor for sepsis morbidity and mortality, and it is associated with elevated baseline levels of circul...

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Detalhes bibliográficos
Main Authors: Shapiro, Nathan I., Khankin, Eliyahu V., Van Meurs, Matijs, Shih, Shou-Ching, Lu, Shulin, Yano, Midori, Castro, Pedro R., Maratos-Flier, Eleftheria, Parikh, Samir M., Karumanchi, S. Ananth, Yano, Kiichiro
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3997057/
https://ncbi.nlm.nih.gov/pubmed/20519646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0903975
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