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A monomer-trimer model supports intermittent glucagon fibril growth

We investigate in vitro fibrillation kinetics of the hormone peptide glucagon at various concentrations using confocal microscopy and determine the glucagon fibril persistence length 60μm. At all concentrations we observe that periods of individual fibril growth are interrupted by periods of stasis....

詳細記述

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書誌詳細
出版年:Sci Rep
主要な著者: Košmrlj, Andrej, Cordsen, Pia, Kyrsting, Anders, Otzen, Daniel E., Oddershede, Lene B., Jensen, Mogens H.
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4355668/
https://ncbi.nlm.nih.gov/pubmed/25758791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep09005
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