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Transient blockade of Delta-like Notch ligands prevents allograft rejection mediated by cellular and humoral mechanisms in a mouse model of heart transplantation

Rejection remains a major clinical challenge limiting allograft survival after solid organ transplantation. Both cellular and humoral immunity contribute to this complication, with increased recognition of antibody-mediated damage during acute and chronic rejection. Using a mouse model of MHC-mismat...

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Bibliografiska uppgifter
I publikationen:J Immunol
Huvudupphovsmän: Wood, Sherri, Feng, Jiane, Chung, Jooho, Radojcic, Vedran, Sandy, Ashley R., Friedman, Ann, Shelton, Amy, Yan, Minhong, Siebel, Christian W., Bishop, D. Keith, Maillard, Ivan
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4355388/
https://ncbi.nlm.nih.gov/pubmed/25687759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402034
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