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Micelle formulation of Hexadecyloxypropyl-Cidofovir (HDP-CDV) as an intravitreal long-lasting delivery system

There still is an unmet need for a safe and sustained intravitreal drug delivery system. In this study we are proposing and characterizing a micelle based, clear-media intravitreal drug delivery system using the lipid derivatized nucleoside analog, hexadecyloxypropyl-cidofovir (HDP-CDV, CMX 001). HD...

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Detalhes bibliográficos
Publicado no:Eur J Pharm Biopharm
Main Authors: Ma, Feiyan, Nan, Kaihui, Lee, SuNa, Beadle, James R., Hou, Huiyuan, Freeman, William R., Hostetler, Karl Y., Cheng, Lingyun
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4355386/
https://ncbi.nlm.nih.gov/pubmed/25513956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejpb.2014.12.010
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