PRMT5 is required for lymphomagenesis triggered by multiple oncogenic drivers

Protein arginine transferase 5(PRMT5) has been implicated as a key modulator of lymphomagenesis. Whether PRMT5 has overt oncogenic function in the context of leukemia/lymphoma and whether it represents a therapeutic target remains to be established. We demonstrate that inactivation of PRMT5 inhibits...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Cancer Discov
Main Authors: Li, Yan, Chitnis, Nilesh, Nakagawa, Hiroshi, Kita, Yoshiaki, Natsugoe, Shoji, Yang, Yi, Li, Zihai, Wasik, Mariusz, Klein-Szanto, Andres J. P., Rustgi, Anil K., Diehl, J. Alan
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4355177/
https://ncbi.nlm.nih.gov/pubmed/25582697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-14-0625
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