Association of the Colorectal CpG Island Methylator Phenotype with molecular features, risk factors and family history

BACKGROUND: The CpG Island Methylator Phenotype (CIMP) represents a subset of colorectal cancers (CRCs) characterized by widespread aberrant DNA hypermethylation at select CpG islands. The risk factors and environmental exposures contributing to etiologic heterogeneity between CIMP and non-CIMP tumo...

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Veröffentlicht in:Cancer Epidemiol Biomarkers Prev
Hauptverfasser: Weisenberger, Daniel J., Levine, A. Joan, Long, Tiffany I., Buchanan, Daniel D., Walters, Rhiannon, Clendenning, Mark, Rosty, Christophe, Joshi, Amit D., Stern, Mariana C., LeMarchand, Loic, Lindor, Noralane M., Daftary, Darshana, Gallinger, Steven, Selander, Teresa, Bapat, Bharati, Newcomb, Polly A., Campbell, Peter T., Casey, Graham, Ahnen, Dennis J., Baron, John A., Haile, Robert W., Hopper, John L., Young, Joanne P., Laird, Peter W., Siegmund, Kimberly D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4355081/
https://ncbi.nlm.nih.gov/pubmed/25587051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-14-1161
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