Association of the Colorectal CpG Island Methylator Phenotype with molecular features, risk factors and family history

BACKGROUND: The CpG Island Methylator Phenotype (CIMP) represents a subset of colorectal cancers (CRCs) characterized by widespread aberrant DNA hypermethylation at select CpG islands. The risk factors and environmental exposures contributing to etiologic heterogeneity between CIMP and non-CIMP tumo...

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Pubblicato in:Cancer Epidemiol Biomarkers Prev
Autori principali: Weisenberger, Daniel J., Levine, A. Joan, Long, Tiffany I., Buchanan, Daniel D., Walters, Rhiannon, Clendenning, Mark, Rosty, Christophe, Joshi, Amit D., Stern, Mariana C., LeMarchand, Loic, Lindor, Noralane M., Daftary, Darshana, Gallinger, Steven, Selander, Teresa, Bapat, Bharati, Newcomb, Polly A., Campbell, Peter T., Casey, Graham, Ahnen, Dennis J., Baron, John A., Haile, Robert W., Hopper, John L., Young, Joanne P., Laird, Peter W., Siegmund, Kimberly D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4355081/
https://ncbi.nlm.nih.gov/pubmed/25587051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-14-1161
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