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Sarcospan integration into laminin-binding adhesion complexes that ameliorate muscular dystrophy requires utrophin and α7 integrin

Duchenne muscular dystrophy (DMD) is caused by mutations in the dystrophin gene that result in loss of the dystrophin–glycoprotein complex, a laminin receptor that connects the myofiber to its surrounding extracellular matrix. Utrophin, a dystrophin ortholog that is normally localized to the neuromu...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Hum Mol Genet
Prif Awduron: Marshall, Jamie L., Oh, Jennifer, Chou, Eric, Lee, Joy A., Holmberg, Johan, Burkin, Dean J., Crosbie-Watson, Rachelle H.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4355028/
https://ncbi.nlm.nih.gov/pubmed/25504048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu615
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